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By Emmanuel Pierrot-Deseilligny, David Burke

Reports of human flow have proliferated lately, and there were many reviews of spinal pathways in people, their function in stream, and their disorder in neurological issues. This complete reference surveys the literature on the topic of the keep watch over of spinal twine circuits in human matters, exhibiting how they are often studied, their function in common circulate, and the way they malfunction in ailment states. Chapters are hugely illustrated and continually organised, reviewing, for every pathway, the experimental historical past, technique, corporation and keep watch over, position in the course of motor initiatives, and adjustments in sufferers with CNS lesions. each one bankruptcy concludes with a priceless resume that may be used independently of the most textual content to supply sensible suggestions for medical experiences. it will be crucial analyzing for study employees and clinicians interested in the research, therapy and rehabilitation of stream problems.

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Extra info for The circuitry of the human spinal cord: its role in motor control and movement disorders

Example text

Ii) Monopolar recordings, with an ‘active’ electrode over the mid-belly of the muscle and a ‘remote’ electrode over its tendon, have been recommended to minimise the effects of changes in geometry of the muscle during voluntary contraction (Gerilovsky, Ysvetinov & Trenkova, 1989). However, these changes are adequately taken into account if the reflex is expressed as a percentage of the maximal M wave (see p. 8) measured under the same conditions. In addition, the more distant the ‘remote’ electrode, the less likely is the recorded activity to come from only the muscle underlying the ‘active’ electrode.

This is due in part to the method of normalising the results but, in addition, there is a different sensitivity of reflexes of different size to facilitation and inhibition, reflecting a non-linear input– output relationship within the motoneurone pool. g. Hunt, 1955; Meinck, 1980). The question was extensively investigated in human subjects and in the cat by Crone et al. (1990), using conditioning stimuli that produce excitation or inhibition at pre- and post-synaptic levels. The distorting effects of normalisation These are illustrated in Fig.

9. Recruitment gain in the motoneurone pool. The input–output relationship for the soleus motoneurone pool is represented at rest (dotted oblique line) and during a possible change in the ‘recruitment gain’ occurring during contraction (dashed oblique line). Inputs: (i) the unconditioned test EPSP (continuous horizontal arrow), (ii) the conditioning femoral EPSP at rest (dotted horizontal arrow) and at the onset of soleus voluntary contraction (dashed horizontal arrow), and the ‘recruitment gain’ of the reflex (= the slope of the relationship).

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