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By Sameer Prakash

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Each virion may contain defective interfering copies. 46 Swine Flu: Diagnosis and Treatment Structure: For an in-depth example. The following applies for Influenza A viruses, although other influenza strains are very similar in structure: The influenza A virus particle or virion is 80-120 nm in diameter and usually roughly spherical, although filamentous forms can occur. 5 kilobases total), which encode 11 proteins (HA, NA, NP, M1, M2, NS1, NEP, PA, PB1, PB1-F2, PB2). The best-characterised of these viral proteins are hemagglutinin and neuraminidase, two large glycoproteins found on the outside of the viral particles.

M encodes two matrix proteins (the M1 and the M2) by using different reading frames from the same RNA segment (about 3000 matrix protein molecules are needed to make one virion). • NS encodes two distinct non-structural proteins (NS1 and NEP) by using different reading frames from the same RNA segment. • PA encodes an RNA polymerase. • PB1 encodes an RNA polymerase and PB1-F2 protein (induces apoptosis) by using different reading frames from the same RNA segment. • PB2 encodes an RNA polymerase.

Transmission may also occur through wild animals, such as wild boar, which can spread the disease between farms. Transmission to Humans People who work with poultry and swine, especially people with intense exposures, are at increased risk of zoonotic infection with influenza virus endemic in these animals, and constitute a population of human hosts in which zoonosis and reassortment can co-occur. Vaccination of these workers against influenza and surveillance for new influenza strains among this population may therefore be an important public health measure.

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