By William C. Faquin MD, PhD, Celeste N. Powers MD, PhD (eds.)
Salivary Gland Cytopathology through William C. Faquin, M.D., Ph.D. and Celeste Powers, M.D., Ph.D., will satisfy the necessity for an easy-to-read and authoritative synopsis of salivary gland cytopathology. This quantity, a part of the Essentials in Cytopathology ebook sequence, matches into the lab coat pocket and is perfect for portability and quickly reference. each one quantity within the sequence is seriously illustrated with a whole colour paintings software, whereas the textual content follows a straightforward define format.
William C. Faquin, MD, PhD, is affiliate Professor of Pathology, division of Pathology, Massachusetts normal clinic, Harvard clinical institution, Boston, Massachusetts.
Celeste N. Powers, MD, PhD, is Professor of Pathology and Otolaryngology, division of Pathology, clinical university of Virginia Hospitals, Virginia Commonwealth collage, Richmond, Virginia.
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Extra resources for Salivary Gland Cytopathology
The latter are approximately the size of lysozomes and appear microscopically as dark purple granules using Papanicolaou and modified H&E stains. The cytoplasm of acinar cells also contains variable numbers of small clear vacuoles that are best appreciated in Diff-Quik preparations (Fig. 6). Nuclei are round and basally located with indistinct nucleoli. Mucinoustype acinar cells are larger and more columnar than the serous 46 4. The Normal Salivary Gland Aspirate Fig. 5. Normal serous-type acinar cells.
Salivary Gland FNA A complete history and focused physical examination is performed to assess the extent of salivary gland disease. Key points to cover include the approximate length of time that the lesion has been present, rate of change in the size of the mass (rapid or slow), associated fever or pain, drug exposures, history of malignancy and chronic illnesses such as rheumatologic disease or sicca syndrome (dry eyes, mouth). Physical examination of a salivary gland lesion is best accomplished with the patient comfortably seated with adequate back and head support.
For diagnostic purposes, it is not important to distinguish between the 3 types of ductal cells present, but their detection is considered a characteristic component of the normal aspirate. Regardless of type, the ductal cells are arranged sometimes in close apposition to the clusters of acinar cells or separately as small honeycomb fragments. Intercalated ductal cells are low cuboidal cells with very scant dense cytoplasm that usually are detected within aspirates as small tubules; they are often directly adjacent to a cluster of acinar cells (Fig.
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