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By H. J. Leese (auth.)

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Extra info for Human Reproduction and in vitro Fertilisation

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As new applications have emerged, new industries have come into being, manufacturing fertility hormones, kits to measure them, embryo culture equipment, surgical apparatus, special refrigerators for freezing embryos etc. A market will surely emerge for techniques used to diagnose genetic diseases. Some view these developments as undesirable. They see reproductive technologies as taking over people's, particularly women's, lives. Others see Aldous Huxley's fantasy Brave New World as coming to fruition with 'glass wombs' and 'embryo farms'.

Chang and 1951 C. R. Austin 1958 Transfer of cultured mouse blastocysts to the uterus of another female followed by birth of live young (A. McLaren and J. D. Biggers) 1959 Unequivocal demonstration of IVF in the rabbit by M. C. Chang 1969 Demonstration of human oocyte fertilisation in vitro by R. G. Edwards, B. D. Bavister and P. C. Steptoe 1972 Successful freezing of mammalian embryos (mouse) described independently by I. Wilmut and D. G. Whittingham 1976 First human pregnancy (ectopic) after IVF and embryo transfer (P.

L Some major events and findings in the history of IVF Aristotle (384-322 BC) writes the first account of embryology 1561 Fallopius gives first correct anatomical description of Fallopian tube 1677 Discovery of mammalian spermatozoa by A. van Leeuwenhoek 1797 Recovery of embryos from rabbit Fallopian tube by W. C. Cruikshank 1827 Identification of an egg in a mammalian ovarian follicle by C. E. von Baer 1875Understanding that fertilisation requires the fusion of one sperm with one 1878 egg by Hertwig (in the sea urchin), Van Beneden (in the rabbit) and Fol (in the starfish) First embryo transfer (in the rabbit) by W.

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