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By Gerald D. Shockman

Chemistry and organic actions of Bacterial floor Amphiphiles.

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24. 25. 26. 27. 28. 29. 30. 31. 32. , and Wicken, A. , Abstr. Annu. Meet. Am. Soc. , p. 158 (1980). , and Salton, M. R. , Biochim. Biophys. Acta 406, 214 (1975). , and Salton, M. R. , Biochim. Biophys. Acta 406, 235 (1975). Higgins, M. L. , Parks, L. C , and Daneo-Moore, L. , in "Organization of Prokaryotic Cell Membranes" (Β. K. Ghosh, e d . ) . Vol. 2, p. 78. CRC Press, Boca Raton, Florida, 1981). , Koch, H. , J. Biol. Chem. 255, 4557 (1980). Silvestri, L. , Craig, R. , Ingram, L. , Hoffmann, Ε.

DE-02901 from the National Institute of Dental Research. Chemistry and Biological Activities of Bacterial Surface Amphiphiles 43 Copyright © 1981 by Academic Press, Inc. All rights of reproduction in any form reserved. ISBN 0-12-640380-5 Arnold S. Bleiweis and Ronald C. Craig 44 II. CHEMICAL ANALYSES OF CRUDE EXTRACTS AND PARTIALLYPURIFIED PRODUCTS Table 1 presents the chemical composition of a typical crude phenol-water extract (iLTA-A) of S. mutans AHT. Large amounts of the cell-wall sugars glucose, galactose and rhamnose are detected.

ISBN 0-12-640380-5 Laura I. Katona et al. 52 case one is interested in how one comDonent influences the other, one should be able to define the components of a mixture. Although the focus of their discussion was the study of the gram-negative amphiphile, lipopolysaccharide (LPS), clearly the same questions arise when studying other bacterial amphiphiles. Are the effects observed, for example, with a particular preparation of lipoteichoic acid (LTA) due solely to the LTA present in the preparation, or due to one of the protein or polysaccharide contaminants?

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